All of the sedative medicines (tranquilizans) developed by medical specialists for the first time in the 19th century are based on potassium bromide. As a side effect, they were not kept very well because they caused excessive saliva production. In 1903, there was a barbiturate-based sleeping medication in Germany called Veronal.
Then the barbiturate compounds began to be used as sedatives. Currently the most widely used sedatives are benzodiazepines.
Valium, Librium and Mogadon are among the best known. These drugs, which have fewer side effects than barbiturate-based drugs, were produced by the Swedish pharmaceutical company Hofmann La Roche in the 1950s.
Calming or sedative It is the general name of the medicine that gives relief to tension and anxiety when used in low dose, sedative effect in feeling and behaviors, and consciousness blur and sleeping drugs in high dose. It slows down the central nervous system. Provides sleep when pharmacologically appropriate dose is used. The sedative effect is weaker than the hypnotic effect. It does not give you sleep. Just calm down. Many sedative drugs show high anesthetic effect. Share Information