The RH Factor An antij was found by Karl Landsteiner and Wiener in 1940 on the red corpus. Rhesus monkey’s blood was used to raise antibodies in the blood sera of rabbit and Indian pig. This antiserum has been observed to account for 80% of human red blood cells in blood when compared to human blood. Clusters of red corpses are said to be Rh positive, that is, individuals possessing this antigen.

Karl Landsteiner strong> He is an Austrian immunologist and pathologist from Austria who lived between 1868 and 1943.

He worked as a researcher at the Vienna Institute of Pathology between 1898-1908, when he worked as a researcher in the blood of humans. and found the risks of inadequate blood transfusions. In 1901, the white blood cells showed that at least three blood groups were present on the inside of the cell membrane, depending on the type of antigens bound to the outer layer of the cell membrane; called these groups A, B, and O.

Landsteiner identified the M and N groups in 1927 as the Rhesus (Rh) factor bearing the name of the monkey rooster for the first time in 1940. Rh factor was the basis for a series of reactions that could occur in maternal and offspring blood, resulting in low, stillbirth and a new, deadly disease.

Landsteiner’s work has contributed significantly to the development of forensic medicine;

The Landsteiner was founded in 1909-1919 at the University of Vienna, where he was a member of the University of Vienna. Between 1922 and 1943 he taught pathology at the Rockefeller Medical Research Institute in New York City. His specific work is the Specificity of Serological Reactions, which contribute to the establishment of immune chemistry.

The Rh factor is important in blood transfusions and blood disorders due to blood incompatibility in newborn infants. In blood transfusions, the blood donor’s blood does not match, leading to very dangerous consequences.

If this person accidentally gives Rh positive blood, the antibodies against it will come into play. Secondly, if this person encounters Rh positive blood, the red blood cells of the transplanted blood are destroyed by these antibodies.

The Rh incompatibility between the mother and the child is as follows: If the mother is Rh negative, if the child is Rh positive, there is usually no problem at first birth. However, if the mother had previously received Rh positive blood transfusions then the child will develop the disease. The main problem is that the second child is Rh-positive. Because, during the first birth, the mother’s blood was exposed to the baby’s blood and antibodies against the Rh factor appeared. These antibodies have the property of passing through the placenta (the child’s “wife” in the middle). These antibodies to the child begin to destroy the child’s red blood cells. Jaundice, generalized edema occurs in the child that does not heal.

Depending on the severity of the blood disorder and the severity of the effect of the antibody, the child may die shortly after birth or at various grades born as jaundiced.

RH Factor

If the mother is Rh (-) and the father is R (+), the medication Rhogam is used to prevent children who are born in danger of blood disagreement from coming into contact with the mother within 48 hours of first birth. Share Multiple Information.

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